Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer
2020 Dhawan, A.; Scott, J.; Sundaresan, P.; Veness, M.; Porceddu, S.; Hau, E.; Harris, A. L.; Buffa, F. M.; Gee, H. E.
Guidelines for using sigQC for systematic evaluation of gene signatures
2019 Dhawan, A.; Barberis, A.; Cheng, W. -C.; Domingo, E.; West, C.; Maughan, T.; Scott, J. G.; Harris, A. L.; Buffa, F. M.
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
2017 Falletta, P.; Sanchez-del-Campo, L.; Chauhan, J.; Effern, M.; Kenyon, A.; Kershaw, C. J.; Siddaway, R.; Lisle, R.; Freter, R.; Daniels, M. J.; Lu, X.; Tuting, T.; Middleton, M.; Buffa, F. M.; Willis, A. E.; Pavitt, G.; Ronai, Z. A.; Sauka-Spengler, T.; Holzel, M.; Goding, C. R.
FANCD2 limits replication stress and genome instability in cells lacking BRCA2
2016 Michl, J.; Zimmer, J.; Buffa, F. M.; Mcdermott, U.; Tarsounas, M.
Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
2010 Buffa, F. M.; Harris, A. L.; West, C. M.; Miller, C. J.
Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project
2018 Robbe, P.; Popitsch, N.; Knight, S. J. L.; Antoniou, P.; Becq, J.; He, M.; Kanapin, A.; Samsonova, A.; Vavoulis, D. V.; Ross, M. T.; Kingsbury, Z.; Cabes, M.; Ramos, S. D. C.; Page, S.; Dreau, H.; Ridout, K.; Jones, L. J.; Tuff-Lacey, A.; Henderson, S.; Mason, J.; Buffa, F. M.; Verrill, C.; Maldonado-Perez, D.; Roxanis, I.; Collantes, E.; Browning, L.; Dhar, S.; Damato, S.; Davies, S.; Caulfield, M.; Bentley, D. R.; Taylor, J. C.; Turnbull, C.; Schuh, A.
Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment
2016 Mehta, S.; Hughes, N. P.; Li, S.; Jubb, A.; Adams, R.; Lord, S.; Koumakis, L.; van Stiphout, R.; Padhani, A.; Makris, A.; Buffa, F. M.; Harris, A. L.
COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment
2014 Generali, D.; Buffa, F. M.; Deb, S.; Cummings, M.; Reid, L. E.; Taylor, M.; Andreis, D.; Allevi, G.; Ferrero, G.; Byrne, D.; Martinotti, M.; Bottini, A.; Harris, A. L.; Lakhani, S. R.; Fox, S. B.
Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts
2013 Kumar, K.; Wigfield, S.; Gee, H. E.; Devlin, C. M.; Singleton, D.; Li, J. -L.; Buffa, F.; Huffman, M.; Sinn, A. L.; Silver, J.; Turley, H.; Leek, R.; Harris, A. L.; Ivan, M.
MicroRNA-10b and breast cancer metastasis
2008 Gee, H. E.; Camps, C.; Buffa, F. M.; Colella, S.; Sheldon, H.; Gleadle, J. M.; Ragoussis, J.; Harris, A. L.
Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells
2012 Favaro, E.; Bensaad, K.; Chong, M. G.; Tennant, D. A.; Ferguson, D. J. P.; Snell, C.; Steers, G.; Turley, H.; Li, J. -L.; Gunther, U. L.; Buffa, F. M.; Mcintyre, A.; Harris, A. L.
Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation
2017 Meier, J. C.; Tallant, C.; Fedorov, O.; Witwicka, H.; Hwang, S. -Y.; Van Stiphout, R. G.; Lambert, J. -P.; Rogers, C.; Yapp, C.; Gerstenberger, B. S.; Fedele, V.; Savitsky, P.; Heidenreich, D.; Daniels, D. L.; Owen, D. R.; Fish, P. V.; Igoe, N. M.; Bayle, E. D.; Haendler, B.; Oppermann, U. C. T.; Buffa, F.; Brennan, P. E.; Muller, S.; Gingras, A. C.; Odgren, P. R.; Birnbaum, M. J.; Knapp, S.
Pre-treatment proliferation and the outcome of conventional and accelerated radiotherapy
2006 Wilson, G. D.; Saunders, M. I.; Dische, S.; Daley, F. M.; Buffa, F. M.; Richman, P. I.; Bentzen, S. M.
Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity
2018 Rodriguez-Berriguete, G.; Granata, G.; Puliyadi, R.; Tiwana, G.; Prevo, R.; Wilson, R. S.; Yu, S.; Buffa, F.; Humphrey, T. C.; Mckenna, W. G.; Higgins, G. S.
Overexpression of POLQ confers a poor prognosis in early breast cancer patients
2010 Higgins, G. S.; Harris, A. L.; Prevo, R.; Helleday, T.; Mckenna, W. G.; Buffa, F. M.
Assessing early therapeutic response to bevacizumab in primary breast cancer using magnetic resonance imaging and gene expression profiles
2011 Mehta, S.; Hughes, N. P.; Buffa, F. M.; Li, S. P.; Adams, R. F.; Adwani, A.; Taylor, N. J.; Levitt, N. C.; Padhani, A. R.; Makris, A.; Harris, A. L.
Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors
2018 Dhawan, A.; Scott, J. G.; Harris, A. L.; Buffa, F. M.
Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer
2015 Leung, W. -Y.; Roxanis, I.; Sheldon, H.; Buffa, F. M.; Li, J. -L.; Harris, A. L.; Kong, A.
Alternate RASSF1 transcripts control SRC activity, E-cadherin contacts, and YAP-mediated invasion
2015 Vlahov, N.; Scrace, S.; Soto, M. S.; Grawenda, A. M.; Bradley, L.; Pankova, D.; Papaspyropoulos, A.; Yee, K. S.; Buffa, F.; Goding, C. R.; Timpson, P.; Sibson, N.; O'Neill, E.
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: The METOXIA consortium
2015 Pettersen, E. O.; Ebbesen, P.; Gieling, R. G.; Williams, K. J.; Dubois, L.; Lambin, P.; Ward, C.; Meehan, J.; Kunkler, I. H.; Langdon, S. P.; Ree, A. H.; Flatmark, K.; Lyng, H.; Calzada, M. J.; Peso, L. D.; Landazuri, M. O.; Gorlach, A.; Flamm, H.; Kieninger, J.; Urban, G.; Weltin, A.; Singleton, D. C.; Haider, S.; Buffa, F. M.; Harris, A. L.; Scozzafava, A.; Supuran, C. T.; Moser, I.; Jobst, G.; Busk, M.; Toustrup, K.; Overgaard, J.; Alsner, J.; Pouyssegur, J.; Chiche, J.; Mazure, N.; Marchiq, I.; Parks, S.; Ahmed, A.; Ashcroft, M.; Pastorekova, S.; Cao, Y.; Rouschop, K. M.; Wouters, B. G.; Koritzinsky, M.; Mujcic, H.; Cojocari, D.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer | 1-gen-2020 | Dhawan, A.; Scott, J.; Sundaresan, P.; Veness, M.; Porceddu, S.; Hau, E.; Harris, A. L.; Buffa, F. M.; Gee, H. E. | SCIENTIFIC REPORTS | - |
| Guidelines for using sigQC for systematic evaluation of gene signatures | 1-gen-2019 | Dhawan, A.; Barberis, A.; Cheng, W. -C.; Domingo, E.; West, C.; Maughan, T.; Scott, J. G.; Harris, A. L.; Buffa, F. M. | NATURE PROTOCOLS | - |
| Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma | 1-gen-2017 | Falletta, P.; Sanchez-del-Campo, L.; Chauhan, J.; Effern, M.; Kenyon, A.; Kershaw, C. J.; Siddaway, R.; Lisle, R.; Freter, R.; Daniels, M. J.; Lu, X.; Tuting, T.; Middleton, M.; Buffa, F. M.; Willis, A. E.; Pavitt, G.; Ronai, Z. A.; Sauka-Spengler, T.; Holzel, M.; Goding, C. R. | GENES & DEVELOPMENT | - |
| FANCD2 limits replication stress and genome instability in cells lacking BRCA2 | 1-gen-2016 | Michl, J.; Zimmer, J.; Buffa, F. M.; Mcdermott, U.; Tarsounas, M. | NATURE STRUCTURAL & MOLECULAR BIOLOGY | - |
| Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene | 1-gen-2010 | Buffa, F. M.; Harris, A. L.; West, C. M.; Miller, C. J. | BRITISH JOURNAL OF CANCER | - |
| Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project | 1-gen-2018 | Robbe, P.; Popitsch, N.; Knight, S. J. L.; Antoniou, P.; Becq, J.; He, M.; Kanapin, A.; Samsonova, A.; Vavoulis, D. V.; Ross, M. T.; Kingsbury, Z.; Cabes, M.; Ramos, S. D. C.; Page, S.; Dreau, H.; Ridout, K.; Jones, L. J.; Tuff-Lacey, A.; Henderson, S.; Mason, J.; Buffa, F. M.; Verrill, C.; Maldonado-Perez, D.; Roxanis, I.; Collantes, E.; Browning, L.; Dhar, S.; Damato, S.; Davies, S.; Caulfield, M.; Bentley, D. R.; Taylor, J. C.; Turnbull, C.; Schuh, A. | GENETICS IN MEDICINE | - |
| Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment | 1-gen-2016 | Mehta, S.; Hughes, N. P.; Li, S.; Jubb, A.; Adams, R.; Lord, S.; Koumakis, L.; van Stiphout, R.; Padhani, A.; Makris, A.; Buffa, F. M.; Harris, A. L. | EBIOMEDICINE | - |
| COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment | 1-gen-2014 | Generali, D.; Buffa, F. M.; Deb, S.; Cummings, M.; Reid, L. E.; Taylor, M.; Andreis, D.; Allevi, G.; Ferrero, G.; Byrne, D.; Martinotti, M.; Bottini, A.; Harris, A. L.; Lakhani, S. R.; Fox, S. B. | BRITISH JOURNAL OF CANCER | - |
| Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts | 1-gen-2013 | Kumar, K.; Wigfield, S.; Gee, H. E.; Devlin, C. M.; Singleton, D.; Li, J. -L.; Buffa, F.; Huffman, M.; Sinn, A. L.; Silver, J.; Turley, H.; Leek, R.; Harris, A. L.; Ivan, M. | JOURNAL OF MOLECULAR MEDICINE | - |
| MicroRNA-10b and breast cancer metastasis | 1-gen-2008 | Gee, H. E.; Camps, C.; Buffa, F. M.; Colella, S.; Sheldon, H.; Gleadle, J. M.; Ragoussis, J.; Harris, A. L. | NATURE | - |
| Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells | 1-gen-2012 | Favaro, E.; Bensaad, K.; Chong, M. G.; Tennant, D. A.; Ferguson, D. J. P.; Snell, C.; Steers, G.; Turley, H.; Li, J. -L.; Gunther, U. L.; Buffa, F. M.; Mcintyre, A.; Harris, A. L. | CELL METABOLISM | - |
| Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation | 1-gen-2017 | Meier, J. C.; Tallant, C.; Fedorov, O.; Witwicka, H.; Hwang, S. -Y.; Van Stiphout, R. G.; Lambert, J. -P.; Rogers, C.; Yapp, C.; Gerstenberger, B. S.; Fedele, V.; Savitsky, P.; Heidenreich, D.; Daniels, D. L.; Owen, D. R.; Fish, P. V.; Igoe, N. M.; Bayle, E. D.; Haendler, B.; Oppermann, U. C. T.; Buffa, F.; Brennan, P. E.; Muller, S.; Gingras, A. C.; Odgren, P. R.; Birnbaum, M. J.; Knapp, S. | ACS CHEMICAL BIOLOGY | - |
| Pre-treatment proliferation and the outcome of conventional and accelerated radiotherapy | 1-gen-2006 | Wilson, G. D.; Saunders, M. I.; Dische, S.; Daley, F. M.; Buffa, F. M.; Richman, P. I.; Bentzen, S. M. | EUROPEAN JOURNAL OF CANCER | - |
| Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity | 1-gen-2018 | Rodriguez-Berriguete, G.; Granata, G.; Puliyadi, R.; Tiwana, G.; Prevo, R.; Wilson, R. S.; Yu, S.; Buffa, F.; Humphrey, T. C.; Mckenna, W. G.; Higgins, G. S. | NUCLEIC ACIDS RESEARCH | - |
| Overexpression of POLQ confers a poor prognosis in early breast cancer patients | 1-gen-2010 | Higgins, G. S.; Harris, A. L.; Prevo, R.; Helleday, T.; Mckenna, W. G.; Buffa, F. M. | ONCOTARGET | - |
| Assessing early therapeutic response to bevacizumab in primary breast cancer using magnetic resonance imaging and gene expression profiles | 1-gen-2011 | Mehta, S.; Hughes, N. P.; Buffa, F. M.; Li, S. P.; Adams, R. F.; Adwani, A.; Taylor, N. J.; Levitt, N. C.; Padhani, A. R.; Makris, A.; Harris, A. L. | JOURNAL OF THE NATIONAL CANCER INSTITUTE | - |
| Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors | 1-gen-2018 | Dhawan, A.; Scott, J. G.; Harris, A. L.; Buffa, F. M. | NATURE COMMUNICATIONS | - |
| Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer | 1-gen-2015 | Leung, W. -Y.; Roxanis, I.; Sheldon, H.; Buffa, F. M.; Li, J. -L.; Harris, A. L.; Kong, A. | ONCOTARGET | - |
| Alternate RASSF1 transcripts control SRC activity, E-cadherin contacts, and YAP-mediated invasion | 1-gen-2015 | Vlahov, N.; Scrace, S.; Soto, M. S.; Grawenda, A. M.; Bradley, L.; Pankova, D.; Papaspyropoulos, A.; Yee, K. S.; Buffa, F.; Goding, C. R.; Timpson, P.; Sibson, N.; O'Neill, E. | CURRENT BIOLOGY | - |
| Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: The METOXIA consortium | 1-gen-2015 | Pettersen, E. O.; Ebbesen, P.; Gieling, R. G.; Williams, K. J.; Dubois, L.; Lambin, P.; Ward, C.; Meehan, J.; Kunkler, I. H.; Langdon, S. P.; Ree, A. H.; Flatmark, K.; Lyng, H.; Calzada, M. J.; Peso, L. D.; Landazuri, M. O.; Gorlach, A.; Flamm, H.; Kieninger, J.; Urban, G.; Weltin, A.; Singleton, D. C.; Haider, S.; Buffa, F. M.; Harris, A. L.; Scozzafava, A.; Supuran, C. T.; Moser, I.; Jobst, G.; Busk, M.; Toustrup, K.; Overgaard, J.; Alsner, J.; Pouyssegur, J.; Chiche, J.; Mazure, N.; Marchiq, I.; Parks, S.; Ahmed, A.; Ashcroft, M.; Pastorekova, S.; Cao, Y.; Rouschop, K. M.; Wouters, B. G.; Koritzinsky, M.; Mujcic, H.; Cojocari, D. | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
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