A total of 323 unique PROMs were recommended for use across 94 COS and 26 disease areas. • 87% of instruments were recommended in only one COS, and each COS included a median of 4.5 instruments. • Overall, global quality of life (25%) and physical functioning (22%) were the most frequently targeted health outcome domains. • A fragmented landscape of recommended PROMs in COS calls for better harmonization of PRO selection and measurement.
Patient-reported outcome measures in core outcome sets targeted overlapping domains but through different instruments
Ciani, Oriana
;Meregaglia, Michela;Fattore, Giovanni
2021
Abstract
A total of 323 unique PROMs were recommended for use across 94 COS and 26 disease areas. • 87% of instruments were recommended in only one COS, and each COS included a median of 4.5 instruments. • Overall, global quality of life (25%) and physical functioning (22%) were the most frequently targeted health outcome domains. • A fragmented landscape of recommended PROMs in COS calls for better harmonization of PRO selection and measurement.
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