Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors
2018 Dhawan, A.; Scott, J. G.; Harris, A. L.; Buffa, F. M.
Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer
2015 Leung, W. -Y.; Roxanis, I.; Sheldon, H.; Buffa, F. M.; Li, J. -L.; Harris, A. L.; Kong, A.
Alternate RASSF1 transcripts control SRC activity, E-cadherin contacts, and YAP-mediated invasion
2015 Vlahov, N.; Scrace, S.; Soto, M. S.; Grawenda, A. M.; Bradley, L.; Pankova, D.; Papaspyropoulos, A.; Yee, K. S.; Buffa, F.; Goding, C. R.; Timpson, P.; Sibson, N.; O'Neill, E.
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: The METOXIA consortium
2015 Pettersen, E. O.; Ebbesen, P.; Gieling, R. G.; Williams, K. J.; Dubois, L.; Lambin, P.; Ward, C.; Meehan, J.; Kunkler, I. H.; Langdon, S. P.; Ree, A. H.; Flatmark, K.; Lyng, H.; Calzada, M. J.; Peso, L. D.; Landazuri, M. O.; Gorlach, A.; Flamm, H.; Kieninger, J.; Urban, G.; Weltin, A.; Singleton, D. C.; Haider, S.; Buffa, F. M.; Harris, A. L.; Scozzafava, A.; Supuran, C. T.; Moser, I.; Jobst, G.; Busk, M.; Toustrup, K.; Overgaard, J.; Alsner, J.; Pouyssegur, J.; Chiche, J.; Mazure, N.; Marchiq, I.; Parks, S.; Ahmed, A.; Ashcroft, M.; Pastorekova, S.; Cao, Y.; Rouschop, K. M.; Wouters, B. G.; Koritzinsky, M.; Mujcic, H.; Cojocari, D.
Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition
2015 Ledaki, I.; Mcintyre, A.; Wigfield, S.; Buffa, F.; Mcgowan, S.; Baban, D.; Li, J. -L.; Harris, A. L.
Science in Focus: Bioinformatics Part 1 – Lost in Translation
2019 O'Cathail, S. M.; Buffa, F. M.
p-Medicine: From data sharing and integration via VPH models to personalized medicine
2011 Rossi, S.; Christ-Neumann, M. L.; Ruping, S.; Buffa, F. M.; Wegener, D.; Mcvie, G.; Coveney, P. V.; Graf, N.; Delorenzi, M.
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU
2010 Favaro, E.; Ramachandran, A.; Mccormick, R.; Gee, H.; Blancher, C.; Crosby, M.; Devlin, C.; Blick, C.; Buffa, F.; Li, J. -L.; Vojnovic, B.; das Neves, R. P.; Glazer, P.; Iborra, F.; Ivan, M.; Ragoussis, J.; Harris, A. L.
Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer
2018 Lord, S. R.; Cheng, W. -C.; Liu, D.; Gaude, E.; Haider, S.; Metcalf, T.; Patel, N.; Teoh, E. J.; Gleeson, F.; Bradley, K.; Wigfield, S.; Zois, C.; Mcgowan, D. R.; Ah-See, M. -L.; Thompson, A. M.; Sharma, A.; Bidaut, L.; Pollak, M.; Roy, P. G.; Karpe, F.; James, T.; English, R.; Adams, R. F.; Campo, L.; Ayers, L.; Snell, C.; Roxanis, I.; Frezza, C.; Fenwick, J. D.; Buffa, F. M.; Harris, A. L.
In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer
2017 Abu-Jamous, B.; Buffa, F. M.; Harris, A. L.; Nandi, A. K.
A machine learning and directed network optimization approach to uncover TP53 regulatory patterns
2023 Triantafyllidis, Charalampos P.; Barberis, Alessandro; Hartley, Fiona; Cuervo, Ana Miar; Gjerga, Enio; Charlton, Philip; van Bijsterveldt, Linda; Rodriguez, Julio Saez.; Buffa, Francesca M.
The many faces of mathematical modelling in oncology
2019 Victori, P.; Buffa, F. M.
Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network
2019 Dhawan, A.; Harris, A. L.; Buffa, F. M.; Scott, J. G.
Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways
2015 Valli, A.; Rodriguez, M.; Moutsianas, L.; Fischer, R.; Fedele, V.; Huang, H. -L.; Van Stiphout, R.; Jones, D.; Mccarthy, M.; Vinaxia, M.; Igarashi, K.; Sato, M.; Soga, T.; Buffa, F.; Mccullagh, J.; Yanes, O.; Harris, A.; Kessler, B.
Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth
2016 Chen, L.; Zeng, X.; Kleibeuker, E.; Buffa, F.; Barberis, A.; Leek, R. D.; Roxanis, I.; Zhang, W.; Worth, A.; Beech, J. S.; Harris, A. L.; Cai, S.
WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma
2023 Coupe, Nicholas; Guo, Lina; Bridges, Esther; Campo, Leticia; Espinosa, Olivia; Colling, Richard; Marshall, Andrea; Nandakumar, Ashwin; van Stiphout, Ruud; Buffa, Francesca M.; Corrie, Pippa G.; Middleton, Mark R.; Macaulay Valentine, M.
The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis
2011 Gee, H. E.; Buffa, F. M.; Camps, C.; Ramachandran, A.; Leek, R.; Taylor, M.; Patil, M.; Sheldon, H.; Betts, G.; Homer, J.; West, C.; Ragoussis, J.; Harris, A. L.
Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma
2013 Betts, G. N. J.; Eustace, A.; Patiar, S.; Valentine, H. R.; Irlam, J.; Ramachandran, A.; Merve, A.; Homer, J. J.; Moller-Levet, C.; Buffa, F. M.; Hall, G.; Miller, C. J.; Harris, A. L.; West, C. M. L.
Depletion of signal recognition particle 72kDa increases radiosensitivity
2017 Prevo, R.; Tiwana, G. S.; Maughan, T. S.; Buffa, F. M.; Mckenna, W. G.; Higgins, G. S.
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis
2010 Jubb, A. M.; Buffa, F. M.; Harris, A. L.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors | 1-gen-2018 | Dhawan, A.; Scott, J. G.; Harris, A. L.; Buffa, F. M. | NATURE COMMUNICATIONS | - |
| Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer | 1-gen-2015 | Leung, W. -Y.; Roxanis, I.; Sheldon, H.; Buffa, F. M.; Li, J. -L.; Harris, A. L.; Kong, A. | ONCOTARGET | - |
| Alternate RASSF1 transcripts control SRC activity, E-cadherin contacts, and YAP-mediated invasion | 1-gen-2015 | Vlahov, N.; Scrace, S.; Soto, M. S.; Grawenda, A. M.; Bradley, L.; Pankova, D.; Papaspyropoulos, A.; Yee, K. S.; Buffa, F.; Goding, C. R.; Timpson, P.; Sibson, N.; O'Neill, E. | CURRENT BIOLOGY | - |
| Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: The METOXIA consortium | 1-gen-2015 | Pettersen, E. O.; Ebbesen, P.; Gieling, R. G.; Williams, K. J.; Dubois, L.; Lambin, P.; Ward, C.; Meehan, J.; Kunkler, I. H.; Langdon, S. P.; Ree, A. H.; Flatmark, K.; Lyng, H.; Calzada, M. J.; Peso, L. D.; Landazuri, M. O.; Gorlach, A.; Flamm, H.; Kieninger, J.; Urban, G.; Weltin, A.; Singleton, D. C.; Haider, S.; Buffa, F. M.; Harris, A. L.; Scozzafava, A.; Supuran, C. T.; Moser, I.; Jobst, G.; Busk, M.; Toustrup, K.; Overgaard, J.; Alsner, J.; Pouyssegur, J.; Chiche, J.; Mazure, N.; Marchiq, I.; Parks, S.; Ahmed, A.; Ashcroft, M.; Pastorekova, S.; Cao, Y.; Rouschop, K. M.; Wouters, B. G.; Koritzinsky, M.; Mujcic, H.; Cojocari, D. | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition | 1-gen-2015 | Ledaki, I.; Mcintyre, A.; Wigfield, S.; Buffa, F.; Mcgowan, S.; Baban, D.; Li, J. -L.; Harris, A. L. | ONCOTARGET | - |
| Science in Focus: Bioinformatics Part 1 – Lost in Translation | 1-gen-2019 | O'Cathail, S. M.; Buffa, F. M. | CLINICAL ONCOLOGY | - |
| p-Medicine: From data sharing and integration via VPH models to personalized medicine | 1-gen-2011 | Rossi, S.; Christ-Neumann, M. L.; Ruping, S.; Buffa, F. M.; Wegener, D.; Mcvie, G.; Coveney, P. V.; Graf, N.; Delorenzi, M. | ECANCERMEDICALSCIENCE | - |
| MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU | 1-gen-2010 | Favaro, E.; Ramachandran, A.; Mccormick, R.; Gee, H.; Blancher, C.; Crosby, M.; Devlin, C.; Blick, C.; Buffa, F.; Li, J. -L.; Vojnovic, B.; das Neves, R. P.; Glazer, P.; Iborra, F.; Ivan, M.; Ragoussis, J.; Harris, A. L. | PLOS ONE | - |
| Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer | 1-gen-2018 | Lord, S. R.; Cheng, W. -C.; Liu, D.; Gaude, E.; Haider, S.; Metcalf, T.; Patel, N.; Teoh, E. J.; Gleeson, F.; Bradley, K.; Wigfield, S.; Zois, C.; Mcgowan, D. R.; Ah-See, M. -L.; Thompson, A. M.; Sharma, A.; Bidaut, L.; Pollak, M.; Roy, P. G.; Karpe, F.; James, T.; English, R.; Adams, R. F.; Campo, L.; Ayers, L.; Snell, C.; Roxanis, I.; Frezza, C.; Fenwick, J. D.; Buffa, F. M.; Harris, A. L. | CELL METABOLISM | - |
| In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer | 1-gen-2017 | Abu-Jamous, B.; Buffa, F. M.; Harris, A. L.; Nandi, A. K. | MOLECULAR CANCER | - |
| A machine learning and directed network optimization approach to uncover TP53 regulatory patterns | 1-gen-2023 | Triantafyllidis, Charalampos P.; Barberis, Alessandro; Hartley, Fiona; Cuervo, Ana Miar; Gjerga, Enio; Charlton, Philip; van Bijsterveldt, Linda; Rodriguez, Julio Saez.; Buffa, Francesca M. | ISCIENCE | - |
| The many faces of mathematical modelling in oncology | 1-gen-2019 | Victori, P.; Buffa, F. M. | BRITISH JOURNAL OF RADIOLOGY | - |
| Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network | 1-gen-2019 | Dhawan, A.; Harris, A. L.; Buffa, F. M.; Scott, J. G. | JOURNAL OF THEORETICAL BIOLOGY | - |
| Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways | 1-gen-2015 | Valli, A.; Rodriguez, M.; Moutsianas, L.; Fischer, R.; Fedele, V.; Huang, H. -L.; Van Stiphout, R.; Jones, D.; Mccarthy, M.; Vinaxia, M.; Igarashi, K.; Sato, M.; Soga, T.; Buffa, F.; Mccullagh, J.; Yanes, O.; Harris, A.; Kessler, B. | ONCOTARGET | - |
| Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth | 1-gen-2016 | Chen, L.; Zeng, X.; Kleibeuker, E.; Buffa, F.; Barberis, A.; Leek, R. D.; Roxanis, I.; Zhang, W.; Worth, A.; Beech, J. S.; Harris, A. L.; Cai, S. | ONCOTARGET | - |
| WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma | 1-gen-2023 | Coupe, Nicholas; Guo, Lina; Bridges, Esther; Campo, Leticia; Espinosa, Olivia; Colling, Richard; Marshall, Andrea; Nandakumar, Ashwin; van Stiphout, Ruud; Buffa, Francesca M.; Corrie, Pippa G.; Middleton, Mark R.; Macaulay Valentine, M. | CELLULAR ONCOLOGY | - |
| The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis | 1-gen-2011 | Gee, H. E.; Buffa, F. M.; Camps, C.; Ramachandran, A.; Leek, R.; Taylor, M.; Patil, M.; Sheldon, H.; Betts, G.; Homer, J.; West, C.; Ragoussis, J.; Harris, A. L. | BRITISH JOURNAL OF CANCER | - |
| Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma | 1-gen-2013 | Betts, G. N. J.; Eustace, A.; Patiar, S.; Valentine, H. R.; Irlam, J.; Ramachandran, A.; Merve, A.; Homer, J. J.; Moller-Levet, C.; Buffa, F. M.; Hall, G.; Miller, C. J.; Harris, A. L.; West, C. M. L. | EUROPEAN JOURNAL OF CANCER | - |
| Depletion of signal recognition particle 72kDa increases radiosensitivity | 1-gen-2017 | Prevo, R.; Tiwana, G. S.; Maughan, T. S.; Buffa, F. M.; Mckenna, W. G.; Higgins, G. S. | CANCER BIOLOGY & THERAPY | - |
| Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis | 1-gen-2010 | Jubb, A. M.; Buffa, F. M.; Harris, A. L. | JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | - |
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