This paper presents a Bayesian nonparametric approach to determining a maximum tolerated dose. Typically, this would be carried out in a phase I trial. We describe a design and analysis which makes use of the Polya tree prior distributions.
A Bayesian nonparametric approach to determining a maximum tolerated dose
MULIERE, PIETRO;
1997
Abstract
This paper presents a Bayesian nonparametric approach to determining a maximum tolerated dose. Typically, this would be carried out in a phase I trial. We describe a design and analysis which makes use of the Polya tree prior distributions.
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